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METOSIL
®
Anti-Emetic
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COMPOSITION
Each
tablet contains Metoclopramide B.P.10mg.
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PROPERTIES
METOSIL
(Metoclopramide HCI.) is a dopamine D2 receptor blocker and harmonizes
gastro duodeno-jejunal motility and increases gastric emptying.
It possesses marked anti-emetic properties. METOSIL exerts a prompt
therapeutic action on a series of gastro-enteric disorders such
as: nausea, vomiting, hiccup, digestive dyskinesias and those observed
during radiological investigations. It does not cause dryness of
the mouth, insomnia, constipation or diarrhea, urinary retention,
disturbance of renal function or alteration in the volume of gastric
secretion.
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INDICATIONS
METOSIL
is used in nausea and vomiting, gastric intolerance to drugs like
antibiotics, digitalis, morphine etc.; gastritis, dyspeptic syndromes,
pyloric spasm, digestive disturbance during cirrhosis and as an
adjuvant therapy in gastric and duodenal ulcers .
It is also used in gastric disorders due to X-Ray, cobalt therapy,
anaesthesia post-operative and chemotherapeutic agents.
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DOSAGE
AND ADMINISTRATION
ADULTS : 1 tablet
three times daily before meals.
CHILDREN : The children's dose should not exceed 0.5 mg/kg body
weight per day .
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CONTRAINDICATIONS
Known hypersensitivity to metoclopramide.
Not recommended during the first trimester of pregnancy. It must
not be administered simultaneously with anti-cholonergics.
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SIDE
EFFECTS
Extrapyramidal symptoms have been reported
with the use of Metoclopramide. Concurrent administration with phenothiazines
may hasten the appearance of extrapyramidal symptoms.
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PRESENTATIONS
METOSIL is available
as 10 mg tablets in packs of 20's and in hospital packs of 1000's.
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